Henry Spira (19 June 1927 – 12 September 1998) was an American activist for socialism and animal rights, who is regarded by some as one of the most effective animal advocates of the 20th century.
Working with Animal Rights International, a group he founded in 1974, Spira is particularly remembered for his successful campaign in 1976 against animal testing at the American Museum of Natural History, where cats were being experimented on for sex research, and for his full-page advertisement in 1980 in The New York Times that featured a rabbit with sticking plaster over the eyes, and the caption, "How many rabbits does Revlon blind for beauty's sake?".